Instructions:

Attached to this assignment, you will find the articles and instructions necessary to complete Assignment 4.1 Applying the Bradford Hill Criteria.

First, you will read the short article about GMOs found at The Generic Literacy Project. (Links to an external site.)This article serves as your example of how to apply the Bradford Hill criteria. As you read, think about how the Bradford Hill criteria were applied to formulate this stance about GMOs. Consider the factors that were identified about GMOs to represent each of the Bradford Hill criteria and, subsequently, form an opinion.

Second, you will read the attached article about a proposed link between French fries and breast cancer. You will then note how the Bradford Hill criteria apply to that article and decide if causation is present based on your application of the Bradford Hill criteria. To complete the assignment, list each of the nine Bradford Hill criteria in a Word document, using the class lecture slides to remind you of the criteria. Next to each one of the criteria, write what you find in the article which corresponds to that criterion–that is, supporting or refuting evidence for each criterion. You may not find evidence for all nine criteria. That is ok. Be sure that you report evidence for at least five of the criteria. After you have noted supporting or refuting evidence for at least five criteria, write a brief summary paragraph stating your conclusion about whether there is a causal link between french fries and breast cancer and why you believe there is or is not based on your application of the Bradford Hill criteria.

Third, you will read the attached article about HPV and cervical cancer. You will apply the Bradford Hill criteria to that article, noting supporting or refuting evidence for each one of the criteria as you did for the previous article. Just as you did before, after noting supporting or refuting evidence for at least five of the Bradford Hill criteria, you will write a brief summary paragraph stating your conclusion about whether there is a causal link between HPV and cervical cancer and why there is or is not based on your application of the Bradford Hill criteria.

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Attachments

• Grading Rubric for Epidemiology Assignments.pdf
• Bradford Hill Case Study.French Fries and Breast Cancer.2006 International_Journal_of_Cancer(1).pdf
• HPV causes cervical cancer.journal article (2015).pdf