1. does somatic hypermutation occur in the central or peripheral
lymphoid organs (or both)?
2. You can find a B cell that matches infection even before it
was ever encountered.
a. yes, with low affinity
b. yes, with high affinity
3. Co-stimulatory signal on the surface of dendritic cell is
induced by:
a. Antigen
b. macrophage signals
C) T lymphocytes





