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Question: A couple (“mom” and “dad”) has a child with a developmental disease (“dd”) and one child with nor…

by | Dec 5, 2023 | Posted Questions

Question: A couple ("mom" and "dad") has a child with a developmental disease ("dd") and one child with nor...

A couple (“mom” and “dad”) has a child with a developmental disease (“dd”) and one child with normal development (“n”). Through clinical tests, the couple is informed that the child with the disease has three copies of chromosome 8. The family’s RFLP analysis (using EcoRI-digested DNA and a labeled probe from chromosome 8) is shown below: A. Explain how RFLP analysis was done to produce the picture above (a step-by- step description is desirable). B. How does the RFLP analysis reveal that the child with the disease has at least three copies of chromosome 8? C. How many chromosomes did the child with the disease get from the mother and the father? D. During which stage of meiosis did a mistake occur to result in a gamete with two different copies chromosomes 8? (a drawing with labeled chromosomes will be helpful here)

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