A. What is probability of producing a plant with genotype ttRRpp? _________ b. What is probability of producing a plant with genotype TtRRPp? ________ C. What in probability of producing a plant with genotype TtRrPP? ______ B. If gene T = Tall, t = dwarf; R = round seeds, r = wrinkled; P = purple flowers, p = white. fill in the phenotypes for each of the predicted genotypes in your Punnett squares on the previous page. What it the probability of producing plants with the following phenotypes? a. tall plants with round seeds and purple flowers _____ b. dwarf plants with round seeds and purple flowers ______ c. tall plants with round seeds and white flower _____ V. Genetics of Human Diseases and Disorders(recessive and dominant autosomal traits) Many genetic diseases and disorders have been studied in humans. The majority of genes that when mutated cause these diseases arc found on autosomes. We will discuss genes on the X chromosome in the section VI. Sex chromosomes – X and Y XX = female, XY = male Autosomes – non-sex chromosomes(chromosome 1 = 22 in humans; 22 pairs of autosomes or 44 autosomes total) Recessive autosomal disease – a recessive mutation in a gene that when present on both homologous chromosomes causes disease Two people heterozygous for a mutation(Aa X Aa)will have a 25% chance of having a child affected by the disease. Affected = aa Unaffected = AA or Aa Carrier – heterozygous individual, Aa(“carries” allele for disease and can pass on to children) Examples of recessive autosomal diseases disorders in humans include: cystic fibrosis, albinism. Tay Sach’s disease, sickle-cell anemia, thalassemia, phenylketonuria, xeroderma pigmentosum Thalassemia is an autosomal recessive disorder causing mild to severe anemia. It is more prevalent in people with ancestors near the Mediterranean, including Southern Europe, North