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Question: As shown in the cross section of an axon to the right, neurofilaments are much more abundant than…

by | Dec 5, 2023 | Posted Questions

Question: As shown in the cross section of an axon to the right, neurofilaments are much more abundant than...

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As shown in the cross section of an axon to the right, neurofilaments are much more abundant than microtubules. Because of the large number of neurofilaments, it might seem more efficient to use these structures for transport in the anterograde (towards the axon tip) and retrograde (towards the cell body) directions. a. What fundamental difference between the structure of microtubules and neurofilaments makes microtubules better suited than neurofilaments as “tracks” for anterograde and retrograde transport? Explain how this structural difference would affect the ability of the two different filaments to provide directional transport in the axon. b. What characteristic(s) allowed the microtubules to be identified in the electron micrograph above? The cross section was not stained with antibodies for the two kinds of proteins. c What motor proteins are used to move materials in the anterograde direction along the microtubules? d. What motor proteins are used to move materials in the retrograde fashion along the microtubule

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