
Consider the following scenario:
Ligand-gated Na+ channels are located in the cell
body of a neuron. Voltage-gated Na+ channels are present all along
the length of the axon. The membrane at the neuron terminus
contains voltage gated Ca++ channels.
a. How would the transmission differ in an axon that is
myelinated? What is meant by the term salutatory conduction?
b.What is the outcome at the neuron terminus, once voltage-gated
Ca++ channels open?
c. With the release of a neurotransmitter, such as
acetylcholine, into the synapse, an electrical signal has been
converted to a chemical signal. What is the effect on the
post-synaptic cell if the acetylcholine receptor is a ligand –gated
sodium channel? The effect of acetylcholine is short lived, given
two mechanisms for the removal of the neurotransmitter from the
synapse. What are these two mechanisms?
Thank you friends
Action potential +40 0 Failed initiations Threshold Resting state 70 Stimulus Refractory period 0 4 Time (ms)





