EXPERIMENT 1: CODING-this is a multiple step question please
answer it step by step.
Post-Lab Questions
Using the red, blue, yellow and green beads, devise and lay out
a three color code (or codon) for each of the following letters
(codon). For example Z = green: red : green.
C: green:blue:green
E: red:green:red
H: green:red:green
I: blue:red:blue
K: green:yellow:green
L: red:blue:red
M: yellow:green:yellow
O: yellow:green:red
S: red:blue:yellow
T: blue:yellow:green
U: blue:yellow:blue
Start: yellow:blue:red
Stop: green:yellow:blue
Space: red:green:yellow
Using your codons, align the beads corresponding to the
appropriate letter to write the following sentence (don’t forget
start, space, and stop): The mouse likes most
cheese
How many beads did you use? 87 beads
There are multiple ways your cells can read a sequence of DNA
and build slightly different proteins from the same strand. We will
not go through the process here, but as an illustration of this
“alternate splicing,” remove codons (beads) 52 – 66 from your
sentence above.
What does the sentence say now? Rewrite the entire
sentence. Does the sentence still make sense?
Mutations are simply changes in the sequence of nucleotides.
There are three ways this occurs:
Change a nucleotide(s)
Remove a nucleotide(s)
Add a nucleotide(s)
Using the sentence from Step 2B:
Change the 24th bead to a different color. What does
the sentence say now? Reread the entire sentence. Does the sentence
still make sense?
Replace the 24th bead and remove the 20th
bead (remember what was there). What does the sentence say? Rewrite
the entire sentence. Does the sentence still make sense? If it
doesn’t make sense as a sentence, are there any words that do? If
so, what words still make sense?
Replace the 20th bead and add one between bead
numbers 50 and 51. What does the sentence say now? Does the
sentence still make sense?
In Step 3a, you mutated one letter. What role do you think the
redundancy of the genetic code plays in this type of change?
Based on your observations, why do you suppose the mutations we
made in Steps 3b and 3c are called frame shift mutations?
Which mutations do you suspect have the greatest consequence?
Why?





