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Question: Hemophilia is a genetic disease that causes affected individuals to have difficulty forming blood…

by | Dec 5, 2023 | Posted Questions

Question: Hemophilia is a genetic disease that causes affected individuals to have difficulty forming blood...

Hemophilia is a genetic disease that causes affected individuals to have difficulty forming blood clots. It is inherited as an X-linked recessive trait. Apparently, certain ancient cultures were aware of this. For example, the Talmud instructs Jews to perform circumcision (surgical removal of the foreskin) on all males except those whose mother’s brother is a “bleeder” (hemophiliac). A. Does this exemption make sense in genetic terms? Why or why not? Explain, using a pedigree. B. There is no similar exemption for a son whose father’s brother is a bleeder. Is this an oversight, or does it make sense in genetic terms? Why or why not? Explain, using a pedigree. C. Should an exemption be made for the son of a mother whose father is bleeder? Explain.

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