Hyperfractionation using a fraction size of 1.2 Gy is replacing a standard 70 gy in 2 Gy fractions for HNSCC. Assume full repair of sublethal damage between fractions. What total dose should be used to maintain the same level of late complications? (Assuming alpha/beta) ratio for late responding tissue is 3 Gy and alpha/beta ratio for tumor is 10 Gy) A. 42 Gy B. 58 Gy C. 70 Gy D. 83 Gy The rationale behind accelerated fractionation is A. To spare late responding normal tissue B. To combat encourage tumor reoxygenation C. To exploit redistribution in tumors D. To combat accelerated repopulation in tumors What is the average malformation rate in humans in the general population without high dose ionizing radiation exposure? A. 1% B. 20% C. 6% D. 10% Small head circumference was observed in some developing human fetuses in Atomic Bomb survivors if the mother and baby were exposed during the fetal stage of development. What was the time period of exposure that this