Please answer the question thoroughly. Go to this link for the
paper. (the graphs don’t necessarily on the paper)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568351/pdf/pnas.201215555.pdf
2.Dr. Oancea presented evidence that the skin can respond to UV light (in particular, she focused on UVA) by a signal transduction cascade that has some similarities and differences compared to the mammalian visual transduction cascade. Based on her paper, answer the following questions alHow does below figure provide evidence that the channel involved in the UV induced transduction cascade is a TRP channel? In other words, what channel is it likely to be and what evidence supports this? (Hint: RR ruthenium red, HC HC-030031. Why are they used here?). UVR 50 pA 2 s vehicle LL 4 RR -60 -40 -20 20 40 60 80 (mv) camphor HC vehicle RR camphor HC Reference: UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes. Nicholas W. Bellono, Laura G. Kammel, Anita L. zimmerman, and Elena Oancea