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Question: Simply define the logic and methods and conclusions from the experiment the authors described bel…

Simply define the logic and methods and conclusions from the
experiment the authors described below in quotes. (*Dont copy and
paste from Google) Make sure to define the terms bolded (4
bolded).

“One possible mechanism for the phenotypes in mitotic
tissues
of D257A mice is a defect in cellular
proliferation. We derived mouse embryonic fibroblast lines
(MEFs)
from D257A and wild-type
littermates and measured the number of
cell doublings before senescence. At 20% oxygen,
both wild-type and D257A MEFs underwent rapid replicative
senescence, whereas neither underwent senescence or reduced growth
after 40 days of culture at 2% oxygen (fig. S9). Thus, accelerated
aging in D257A mice is not likely to be due to an intrinsic defect
in cellular proliferation, or to accelerated cellular
senescence.”

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