The trp-cage protein is a tiny protein with a 20 amino acid
sequence. The sequence (starting from the N terminus) is
NLYIQWLKDGGPSSGRPPPS
a. Using the sequence, write the mRNA code corresponding to
trp-cage. Write it in the 5’-3’ direction.
b. Write the DNA sequence corresponding to the trp-cage. Specify
the 5’-3’ direction.
c. Explain the steps from transcription to translation to
generate trp-cage from the original DNA sequence. Be specific about
direction (5’-3’) in which mRNA comes off of the DNA. Show where a
small piece of the mRNA is complementary to the original DNA in the
correct direction. Where in the cell do these steps take place?
Basically, demonstrate that you fully understand exactly how
transcription and translation take place. You do NOT need to name
every enzyme. Just the major ones.
d. There are no introns in DNA sequence you derived from the
known protein structure. Why not?





