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Question: While studying vesicle transport in the axons of Wild-type, neural cells, you observe that vesicl…

by | Dec 5, 2023 | Posted Questions

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Question: While studying vesicle transport in the axons of Wild-type, neural cells, you observe that vesicl...

While studying vesicle transport in the axons of Wild-type, neural cells, you observe that vesicles are transported in two directions-away from and towards the cell body. You propose two models to explain this behavior: A. The vesicles are transported by one type of motor protein, kinesin. B. Microtubules are arranged in two directions along the axon, some with the plus ends facing away from the cell body, and some with plus ends facing towards the cell body. A. The vesicles are transported by two motor proteins, kinesin and dynein. B. Microtubules are arranged in one direction along the axon, with plus ends facing away from the cell body. To distinguish between these models, you create a mutant cell line in which the genes for dynein motors have been deleted. A. In this mutant cell line, do you predict that vesicles would move in one or two directions if Model 1 is accurate? Please explain your reasoning. B. In this mutant cell line, do you predict that vesicles would move in one or two directions if Model 2 is accurate? Please explain your reasoning.

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